Maitake Extract Scientific References
Deng G, Lin H, Seidman A, Fornier M, D’Andrea G, Wesa K, Yeung S, Cunningham-Rundles S, Vickers AJ, Cassileth B (2009) A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects. J Cancer Res Clin Oncol 135:1215–1221
Hishida, I., H. Nanba, and H. Kuroda. 1988. Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa (maitake).Chem. Pharm. Bull. (Tokyo) 36:1819–1827.
Harada, N., N. Kodama, and H. Nanba. 2003. Relationship between dendritic cells and the D-fraction-induced Th-1 dominant response in BALB/c tumor-bearing mice. Cancer Lett. 192:181–187.
Ito K, Masuda Y, Yamasaki Y, Yokota Y, Nanba H (2009) Maitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression. Int Immunopharmacol
Inoue, A., N. Kodama, and H. Nanba. 2002. Effect of maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion. Biol. Pharm. Bull. 25:536–540.
Kodama N, Harada N, Nanba H. A polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice. Jpn J Pharmacol 2002;90:357–60.
Kodama N, Komuta K, Sakai N, Nanba H. Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells. Biol Pharm Bull 2002;25:1647–50.
Kodama, N., A. Asakawa, A. Inui, Y. Masuda, and H. Nanba. 2005. Enhancement of cytotoxicity of NK cells by D-fraction, a polysaccharide from Grifola frondosa. Oncol. Rep. 13:497–502.
Kodama N, Murata Y, Asakawa A, Inui A, Hayashi M, Sakai N, et al. Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice. Nutrition 2005;21:624–9.
Lin, H., Y. H. She, B. R. Cassileth, F. Sirotnak, and S. Cunningham Rundles. 2004. Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro. Int. Immunopharmacol. 4:91–99.
Lin H, She YH, Cassileth BR, Sirotnak F, Cunningham Rundles S (2004) Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro. Int Immunopharmacol 4:91–99
Lin H, Cheung SW, Nesin M, Cassileth BR, Cunningham-Rundles S (2007) Enhancement of umbilical cord blood cell hematopoiesis by maitake beta-glucan is mediated by granulocyte colony-stimulating factor production. Clin Vaccine Immunol 14:21–27
Lin H, De Stanchina E, Zhou XK, She YH, Hoang D, Cheung SW, Cassileth BR, Cunningham-Rundles S (2009) Maitake betaglucan enhances umbilical cord blood stem cell transplantation in the NOD/SCID mouse. Exp Biol Med (Maywood) 234:342–353
Masuda Y, Murata Y, Hayashi M, Nanba H. Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesionmolecule (ICAM)-1 expression in lung vascular endothelial cells. Biol Pharm Bull 2008;31(6):1104–8.
Masuda, Y., Ito, K., Konishi, M., Nanba, H. A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer. Cancer Immunology, Immunotherapy 59 (10), pp. 1531-1541
Nanba, H., A. Hamaguchi, and H. Kuroda. 1987. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem. Pharm. Bull. (Tokyo) 35:1162–1168.
Nanba, H., and K. Kubo. December 1998. Antitumor substance extracted from grifola. U. S. patent 5,854,404. 25. Ohno, N., K. Saito, J. Nemoto, S. Kaneko,
Hishida, I., H. Nanba, and H. Kuroda. 1988. Antitumor activity exhibited by orally administered extract from fruit body of Grifola frondosa (maitake).Chem. Pharm. Bull. (Tokyo) 36:1819–1827.
Harada, N., N. Kodama, and H. Nanba. 2003. Relationship between dendritic cells and the D-fraction-induced Th-1 dominant response in BALB/c tumor-bearing mice. Cancer Lett. 192:181–187.
Ito K, Masuda Y, Yamasaki Y, Yokota Y, Nanba H (2009) Maitake beta-glucan enhances granulopoiesis and mobilization of granulocytes by increasing G-CSF production and modulating CXCR4/SDF-1 expression. Int Immunopharmacol
Inoue, A., N. Kodama, and H. Nanba. 2002. Effect of maitake (Grifola frondosa) D-fraction on the control of the T lymph node Th-1/Th-2 proportion. Biol. Pharm. Bull. 25:536–540.
Kodama N, Harada N, Nanba H. A polysaccharide, extract from Grifola frondosa, induces Th-1 dominant responses in carcinoma-bearing BALB/c mice. Jpn J Pharmacol 2002;90:357–60.
Kodama N, Komuta K, Sakai N, Nanba H. Effects of D-Fraction, a polysaccharide from Grifola frondosa on tumor growth involve activation of NK cells. Biol Pharm Bull 2002;25:1647–50.
Kodama, N., A. Asakawa, A. Inui, Y. Masuda, and H. Nanba. 2005. Enhancement of cytotoxicity of NK cells by D-fraction, a polysaccharide from Grifola frondosa. Oncol. Rep. 13:497–502.
Kodama N, Murata Y, Asakawa A, Inui A, Hayashi M, Sakai N, et al. Maitake D-Fraction enhances antitumor effects and reduces immunosuppression by mitomycin-C in tumor-bearing mice. Nutrition 2005;21:624–9.
Lin, H., Y. H. She, B. R. Cassileth, F. Sirotnak, and S. Cunningham Rundles. 2004. Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro. Int. Immunopharmacol. 4:91–99.
Lin H, She YH, Cassileth BR, Sirotnak F, Cunningham Rundles S (2004) Maitake beta-glucan MD-fraction enhances bone marrow colony formation and reduces doxorubicin toxicity in vitro. Int Immunopharmacol 4:91–99
Lin H, Cheung SW, Nesin M, Cassileth BR, Cunningham-Rundles S (2007) Enhancement of umbilical cord blood cell hematopoiesis by maitake beta-glucan is mediated by granulocyte colony-stimulating factor production. Clin Vaccine Immunol 14:21–27
Lin H, De Stanchina E, Zhou XK, She YH, Hoang D, Cheung SW, Cassileth BR, Cunningham-Rundles S (2009) Maitake betaglucan enhances umbilical cord blood stem cell transplantation in the NOD/SCID mouse. Exp Biol Med (Maywood) 234:342–353
Masuda Y, Murata Y, Hayashi M, Nanba H. Inhibitory effect of MD-Fraction on tumor metastasis: involvement of NK cell activation and suppression of intercellular adhesionmolecule (ICAM)-1 expression in lung vascular endothelial cells. Biol Pharm Bull 2008;31(6):1104–8.
Masuda, Y., Ito, K., Konishi, M., Nanba, H. A polysaccharide extracted from Grifola frondosa enhances the anti-tumor activity of bone marrow-derived dendritic cell-based immunotherapy against murine colon cancer. Cancer Immunology, Immunotherapy 59 (10), pp. 1531-1541
Nanba, H., A. Hamaguchi, and H. Kuroda. 1987. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem. Pharm. Bull. (Tokyo) 35:1162–1168.
Nanba, H., and K. Kubo. December 1998. Antitumor substance extracted from grifola. U. S. patent 5,854,404. 25. Ohno, N., K. Saito, J. Nemoto, S. Kaneko,
